POST-TETANIC POTENTIATION IN GANGLIA WHICH ARE BLOCKED WITH HEXAMETHONIUM
نویسندگان
چکیده
منابع مشابه
Post-tetanic potentiation in Aplysia sensory neurons.
Post-tetanic potentiation (PTP) lasting several minutes is produced by high frequency intracellular activation of mechanosensory neurons. Control procedures suggest that the PTP involves a homosynaptic mechanism, restricted to the active synapses. The capacity for PTP appears to be a general property of mechanosensory neurons in this animal since it is found in separate sensory populations inne...
متن کاملEarly and Late Post-tetanic Potentiation, and Post-tetanic Block in a Monosynaptic Reflex Pathway
Observations have been made upon the nature of early and late post-tetanic potentiation and upon post-tetanic block of presynaptic collaterals with particular reference to behavior in circumstances of varied duration and frequency of conditioning stimulation. Early potentiation is most conspicuous following brief tetani at high frequency, late potentiation following long tetani, much lower freq...
متن کاملEarly and Late Post-tetanic Potentiation, and Post-tetanic Block in a Monosynaptic Reflex Pathway By
Observations have been made upon the nature of early and late post-tetanic potentiation and upon post-tetanic block of presynaptic collaterals with particular reference to behavior in circumstances of varied duration and frequency of conditioning stimulation. Early potentiation is most conspicuous following brief tetani at high frequency, late potentiation following long tetani, much lower freq...
متن کاملOn the mechanism by which phenytoin blocks post-tetanic potentiation at the frog neuromuscular junction.
Post-tetanic potentiation (PTP) was elicited at the frog sartorius and cutaneous pectoris neuromuscular junctions. A 30-sec, 30-Hz tetanus produced a 2- to 3-fold post-tetanic increase in endplate potential (EPP). In surface-recorded responses this PTP decayed in a double exponential way with time constants of 12.7 sec +/- 2.4 (SEM) and 146.8 sec +/- 36.6. In acute experiments 0.2 to 0.8 mM phe...
متن کاملMitochondrial Involvement in Post-Tetanic Potentiation of Synaptic Transmission
Posttetanic potentiation (PTP) is an essential aspect of synaptic transmission that arises from a persistent presynaptic [Ca2+]i following tetanic stimulation. At crayfish neuromuscular junctions, several inhibitors of mitochondrial Ca2+ uptake and release (tetraphenylphosphonium or TPP+, carbonyl cyanide m-chlorophenylhydrazone or CCCP, and ruthenium red) blocked PTP and the persistence of pre...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1980
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1980.tb07897.x